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Oxycodone is a semisynthetic opioid synthesized from thebaine, an opioid alkaloid found in the Persian poppy, and one of the many alkaloids found in the opium poppy.
Solubility in water: HCl: 166 mg/mL (20 °C)
Onset of action: 10–30 minutes (IR); 1 hour (CR)
Duration of action: 3–6 hours (IR) (variable); 12 hours (CR)
Trade name: many
Biological half-life: 2–3 hours (IR) (variable) (same t1/2 for all ROAs); 4.5 hours (CR)
Oxycodone comes as a solution (liquid), a concentrated solution, a tablet, a capsule, an extended-release (long-acting) tablet (Oxycontin) and an extended-release capsule (Xtampza ER) to take by mouth. The solution, concentrated solution, tablet, and capsule are taken usually with or without food every 4 to 6 hours, either as needed for pain or as regularly scheduled medications. The extended-release tablets (Oxycontin) are taken every 12 hours with or without food. The extended-release capsules (Xtampza ER) are taken every 12 hours with food; eat the same amount of food with each dose. Follow the directions on your prescription label carefully. Take oxycodone exactly as directed.
If you are taking Oxaydo brand tablets, swallow the tablets one at a time with plenty of water. Swallow the tablet or right after putting it in your mouth. Do not presoak, wet, or lick the tablets before you put them in your mouth. Do not chew or crush Oxaydo brand tablets. and do not give them through a nasogastric tube (NG tube; a tube threaded through the nose to deliver food and medication directly to the stomach).
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If you have trouble swallowing extended-release capsules (Xtampza ER), you can carefully open the capsule and sprinkle the contents on soft foods such as applesauce, pudding, yogurt, ice cream, or jam, then consume the mixture immediately. Dispose of the empty capsule shells right away by flushing them down a toilet. Do not store the mixture for future use.
If you have a feeding tube, the extended-release capsule contents can be poured into the tube. Ask your doctor how you should take the medication and follow these directions carefully. Oxycodone – pain meds overnight delivery – buy Oxycodone online
If you are taking the concentrated solution, your doctor may tell you to mix the medication in a small amount of juice or semisolid food such as pudding or applesauce. Follow these directions carefully. Swallow the mixture right away; do not store it for later use.
Your doctor will likely start you on a low dose of oxycodone and may increase this dose over time if your pain is not controlled. After you take oxycodone for a period of time, your body may become used to the medication. If this happens, your doctor may need to increase your dose to control your pain. Your doctor may decrease your dose if you experience side effects. Talk to your doctor about how you are feeling during your treatment with oxycodone. Oxycodone – pain meds overnight delivery – buy Oxycodone online
Do not stop taking oxycodone without talking to your doctor. If you stop taking this medication suddenly, you may experience withdrawal symptoms such as restlessness, watery eyes, runny nose, sneezing, yawning, sweating, chills, muscle or joint aches or pains, weakness, irritability, anxiety, depression, difficulty falling asleep or staying asleep, cramps, nausea, vomiting, diarrhea, loss of appetite, fast heartbeat, and fast breathing. Your doctor will probably decrease your dose gradually. Oxycodone – pain meds overnight delivery – buy Oxycodone online
What side effects can this medication cause?
Oxycodone may cause side effects. Tell your doctor if any of these symptoms, are severe or do not go away:
- dry mouth
- stomach pain
- mood changes
Some side effects can be serious. If you experience any of these symptoms or those mentioned in the IMPORTANT WARNING section, call your doctor immediately or get emergency medical help:
- changes in heartbeat
- agitation, hallucinations (seeing things or hearing voices that do not exist), fever, sweating, confusion, fast heartbeat, shivering, severe muscle stiffness or twitching, loss of coordination, nausea, vomiting, or diarrhea
- nausea, vomiting, loss of appetite, weakness, or dizziness
- inability to get or keep an erection
- irregular menstruation
- decreased sexual desire
- chest pain
- swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- difficulty breathing or swallowing
- extreme drowsiness
- lightheadedness when changing positions
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program by phone (1-800-332-1088).
Oxycodone may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.
How do I safely store opioids?
The abuse of opioids is a significant public safety concern. Teenagers and young adults most commonly get these medicines from their own medicine cabinets, where another family member has stored them.
All opioids should be stored in their original packaging inside a locked cabinet, lockbox, or a location where others cannot easily access them.
Carefully note when and how much medicine you take in order to keep track of how much is left.
If you think that someone has taken your medicine, contact the police immediately to file a report.
How do I safely dispose of Oxycodone?
Many communities have medicine take-back programs. Ask your family doctor for more information or visit the U.S. Drug Enforcement Administration’s Office of Diversion Control to learn more. You can also call your local waste management company to ask if there is a take-back program in your community. Oxycodone – pain meds overnight delivery – buy Oxycodone online
Oxycodone pill often come with instructions for flushing unused medicine to prevent unintentional use or illegal abuse.
The FDA recommends always flushing used and leftover pain patches down the toilet. Even used patches still have enough medicine in them to be dangerous or deadly to pets, children, and others with a low tolerance for opioids. To dispose of a pain patch, fold it in half so the sticky sides stick together, then flush it immediately.
What if my community doesn’t allow flushing unused pills?
If your community warns against flushing unused medicines down the toilet, take the following steps instead:
- Remove personal information from the prescription label and keep the medicine in its original container.
- Add water to solid pills. Also add a nontoxic and unpalatable substance, such as coffee grounds or kitty litter to the container.
- Seal the container with duct tape and place inside a second, unmarked container, then place in the trash.
If you are not sure about how to dispose of a medicine, ask your doctor.